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Conclusion Active GLP-1 is a gut hormone derived as a result of proglucagon processing 1,2

The intermediate products and related enzymes of glutathione metabolism may be involved in other metabolic processes, reflecting the complexity and integrity of the cellular metabolic network ( Figure 10 )

Supplementation with GSH is generally ineffective at increasing cellular glutathione levels because most human cells cannot uptake extracellular GSH due to the lack of the membrane-bound ectoenzyme -glutamyltranspeptidase (-GT) or due to an unfavorable concentration gradient across the cell membrane 10,16

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