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In both in vivo and ex vivo models of myocardial ischemic injury, GLP-1(2836) prevented cardiac dysfunction, reduced infarct size, and protected coronary vascular cells from oxidative stress injury

Semaglutide is a glucagon-like peptide-1 (GLP-1) analog that was FDA-approved in 2017 for treatment of type II diabetes and in 2021 for treatment for chronic weight management in adults with obesity or overweight with at least one weight-related condition

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