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However, obese individuals are characterised by tissue resistance to leptin, as a result of which their bodies produce more leptin [93]

Because it originates in gastric juice, its natural target tissues are the stomach, small intestine, and colon

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2.1.1 Planning A protocol was developed and discussed by the author team to guide the stages of the SR, incorporating essential information such as the article title, authors, objectives, keywords, research questions, sources of research, inclusion/exclusion criteria, search strings, selection of databases, and quality assessment of collected files