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Its an NDRI, which stands for norepinephrine-dopamine reuptake inhibitor

However, the potential for GLP-1R endocytosis to influence pharmacodynamics of exendin-4 has previously been modelled (Gao and Jusko, 2012), and whilst this model focussed on receptor internalisation, differences in recycling and degradation rates could plausibly be linked via similar mechanisms

174 However, SIRT1 has been found to be upregulated in several human cancers