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Zunica ER, Yang S, Coulter A, White C, Kirwan JP, Gilmore LA

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Respiratory Research The lungs exposure to environmental oxidants makes pulmonary GSH research particularly important: Acute Lung Injury Models: Investigation of GSH-mediated protection against oxidant-induced lung injury COPD Research: Studies on lung GSH depletion in chronic obstructive pulmonary disease models Asthma Studies: Examination of airway GSH levels and oxidative stress in allergic airway inflammation Pulmonary Fibrosis: Research on GSH status and oxidative mechanisms in lung fibrosis development Air Pollution Studies: Investigation of GSH response to ozone, particulate matter, and cigarette smoke exposure Acute Respiratory Distress Syndrome: Analysis of lung GSH depletion in ARDS pathophysiology Cystic Fibrosis Research: Studies on airway GSH deficiency and oxidative stress in CF models Research protocols examine bronchoalveolar lavage fluid GSH, lung tissue GSH measurements, epithelial lining fluid analysis, and respiratory function testing