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This may be due to its effect on lowering TG as a result of changes in lipoprotein composition, which is damaged in diabetes.[] These different results may be caused by the difference in the types of studies conducted,[ , ] the way in which they were designed, and the duration of intervention applied.[] Also, TG levels may increase due to an elevated amount of fatty acids and Apo B100 that can lead to increased VLDL production.[] However, L-carnitine may in fact decrease TG levels

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The IDH2 enzyme is also a homodimeric enzyme but is located in the mitochondria

For instance, the mitochondrial shuttle-system allows the transport of fatty acids, as acylcarnitines, from the cytosol into the mitochondrial matrix where these nutrients are oxidized for ATP production