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These three clusters are not influenced by age at first DE onset, cumulative duration, or types of depression, but it is cerebrovascular and cardiovascular diseases and physical symptoms associated with them, i.e

Key end points included: hospitalisation, heart failure (ICD-10-CM-I50), myocardial infarction (ICD-10-CM-I21), stroke and transient ischaemic attack (ICD-10-CM-I63, G45), development of diabetic microvascular complications (ICD-10-CM-E10.210.4) and all-cause mortality analysed 3 months to 5 years post drug initiation