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To date, these GLP-1 drugs have been approved to treat three adult populations: individuals with type 2 diabetes, individuals with a body mass index (BMI) of 30 or greater (obesity), and individuals with a BMI between 27 and 30 (overweight) with at least one weight-related health condition, such as cardiovascular disease, high blood pressure, high cholesterol, prior stroke, prior heart attack, and chest pain (angina)
Sex and gender differences in stress circuits, autonomic regulation and immune responses contribute to distinct patterns of neurological and cardiovascular diseases
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It is normally produced only in small amounts, and then almost immediately detoxified in the liver
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