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Deposition of cholesterol in the intima of arteries induces endothelium to produce VCAM-1 50 which appears to be cytokine dependent as the presence of TNF- in the smooth muscle cells is associated with an increase expression of VCAM-1 51

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Early identification through testing is important, as insulin resistance is largely asymptomatic until complications develop

A new meta-analysis just published in The Lancet Diabetes & Endocrinology is the largest ever conducted on individual-level data evaluating the glycemic effects of statins