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In women, the hormonal changes of menopause typically increase LDL cholesterol and ApoB while worsening particle distribution, and hormone optimization may provide lipid benefits, though effects are variable and individualized

For cetirizine and other antihistamines, the following formulation guidance applies: Sugar-free oral solutions are typically the first-line recommendation in the immediate post-operative period (usually the first 46 weeks) sugar-free formulations are preferred to minimise the risk of osmotic diarrhoea or dumping symptoms Standard immediate-release tablets (not modified-release or enteric-coated) are generally acceptable once the patient has progressed to a soft or normal diet Modified-release preparations should be avoided where possible, as their controlled-release mechanism may be disrupted by altered gastrointestinal transit this principle applies to all modified-release medicines, not just antihistamines Dispersible tablets can be a practical alternative if liquid formulations are unavailable, but confirm suitability with a pharmacist first, as some film-coated tablets may taste unpleasant when crushed or dispersed Other commonly used antihistamines in the UK include loratadine (Clarityn) and fexofenadine (Telfast)

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