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The glucagonlike peptide 1 analogue exendin4 attenuates the nicotineinduced locomotor stimulation, accumbal dopamine release, conditioned place preference as well as the expression of locomotor sensitization in mice

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Lillys orforglipron, a once-daily pill, posted Phase 3 wins in T2D and obesity: according to the New England Journal of Medicine, in a head-to-head T2D study, orforglipron cut A1C by 2.2% vs 1.4% for oral semaglutide

Defective mitophagy in aged macrophages promotes mitochondrial DNA cytosolic leakage to activate STING signaling during liver sterile inflammation