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IRE1 inhibition with KIRA6 or 48C reduces ER stress, neuronal death, and tau aggregation in PD, ALS, and AD models

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Weina H, Yuhu N, Christian H, Birong L, Feiyu S, Le W

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Cysteine S-conjugate -lyases: important roles in the metabolism of naturally occurring sulfur and selenium-containing compounds, xenobiotics and anticancer agents

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In preclinical models, this translates to measurably faster healing of tendons, ligaments, muscles, and GI tissue

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