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While the protection of normal cells against radiation-induced cell death by ebselen has been attributed to its ability to detoxify cellular/mitochondrial ROS through the GPx mechanism, the molecular mechanism contributing to its radio-sensitization effect in cancer cells is still not fully understood
Individuals under 18, pregnant or nursing individuals, or those with active medical conditions - per the brand's own label caution, physician consultation is recommended before use in these groups
When to seek medical advice : Patients should contact their healthcare provider if nausea prevents adequate fluid or protein intake for more than 24 hours, if vomiting occurs more than 2-3 times daily, or if signs of dehydration develop (decreased urination, dizziness, extreme fatigue)
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