While the pathways through which ER stress and the UPR regulate mitochondrial function are becoming clearer, the conversehow mitochondrial function impacts ER homeostasisis less understood
IUBMB Life 70(7):585592 Ballatori N, Krance SM, Marchan R, Hammond CL (2009) Plasma membrane glutathione transporters and their roles in cell physiology and pathophysiology
Moreover, they found that folic acid could repress ferroptosis in nucleus pulposus cells by downregulating the methylation level of GPX4 [151]
Downstream molecules regulated by ncRNAs, P53, HSPB1, NRF2, and NOX2, key regulators of ferroptosis, are also involved in the regulation of other cell death types [65], suggesting that ferroptosis and other types of cell death are independent and related