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However, at high supra-physiologic doses you can potentially experience side effects: Daytime drowsiness Vivid dreams and nightmares Feelings of depression and anxiety Headaches Nausea Changes in blood pressure Children most often experience morning drowsiness as a side effect of melatonin

Animal studies have reported reduced offspring weight, but it is unclear whether this was due to the medication, maternal weight loss, or other factors

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[6] demonstrated how doxycycline can protect against sepsis by inducing disease tolerance without diminishing bacterial load in a mouse model of bacterial sepsis