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These Authors failed to evidence significant changes in indexes of insulin resistance and speculated that other classical effects of GLP-1 RA, such as suppressed glucagon secretion, with consequent reduced hepatic glucose production, could have been involved in the improvement in glucose metabolism and ectopic fat deposition [54]

This mechanism not only aids in weight loss but also offers additional benefits such as improved insulin sensitivity and reduced appetite, contributing to overall metabolic health

Hormonal Fluctuation Potentials: Transitioning can temporarily disrupt carefully balanced systemic thyroid-stimulating hormone levels