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Apoptosis and necrosis of senescent chondrocytes After culturing with CuS and B2M-CuS NPs (50 g mL 1 ) for 24 h, senescent ATDC5 cells were collected and incubated with 100 L of Annexin V-FITC and PI solution (BD, USA) for 20 min at RT

[DOI] [PMC free article] [PubMed] [Google Scholar] 33.Garikipati VN, Singh SP, Mohanram Y, Gupta AK, Kapoor D, Nityanand S, et al

In such a situation, the ablation of GPx4 has been demonstrated to render tumor cells more susceptible to ferroptosis-eliciting agents, suggesting that GPx4 may emerge as a promising target for the development of novel therapeutic interventions (181, 182)