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10.1186/1742-2094-8-117 J

BatraRArnoldMWrheideMAAllenMWangXBlachCet al

Without sufficient methyl donor availability, the liver's capacity to clear incoming fatty acids becomes rate-limited, and triglycerides accumulate intracellularly

The antinociceptive effect of ALC is mediated by increases in the expression of metabotropic glutamate receptor 2 (mGlu2) in the regions of CNS connected with pain transmission via an epigenetic mechanism involving the acetylation of the p65/NFkB complex [26]