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The dose starts low and gradually increases over several weeks

As scientific knowledge expanded, researchers began exploring ways to create synthetic peptides that could mimic or enhance naturally occurring biological processes

3 Nature, 2011

Adverse events, including pancreatitis, were not different between the groups, except that more patients in the saxagliptin group (3.5%) than in the placebo group (2.8%) were hospitalized for heart failure (94)