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These advancements position microneedle technology as a transformative approach for delivering GLP-1 receptor agonists, offering the potential to improve therapeutic adherence, minimize systemic side effects, and support decentralized care models for diabetes management [43]

After all, Aristotle wrote in the fourth century BCE that many people, when they want to cool water quickly, begin by putting it in the sun, the benefits of which were presumably noticeable even before the invention of sensitive thermometers

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