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Prolactinomas in pregnancy: considerations before conception and during pregnancy

The hallmarks of sciatica pain include: Searing pain in your lower back that can come and go with certain movements Pain that radiates down one side of your buttocks, hips, and legs Dull pain in your back, hips, and buttocks Numbness or tingling anywhere along the nerve Weakness in your leg The characteristics of your pain can vary, depending upon which nerve root is compressed or pinched

Nijhout HF, Reed MC, Budu P, Ulrich CM

These insights allow clinicians to anticipate which patients are more likely to respond robustly to tirzepatide and which may benefit from dose adjustments or complementary approaches