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Key characteristics: Short sequence length (16 amino acids), relatively straightforward to synthesise at high purity Frequently referenced in literature discussing mitochondrial-nuclear communication the concept that mitochondria may signal to the rest of the cell via peptides they encode Studied in metabolic research models exploring cellular energy regulation pathways AOD9604: A Modified Fragment of Human Growth Hormone AOD9604 is a synthetic peptide corresponding to a modified fragment of the C-terminus of human growth hormone (specifically, the region historically referred to as the GH fragment 176-191, with a modified terminus for stability)

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CEO David Ricks highlighted progress on orforglipron, an oral GLP-1 candidate that completed four Phase 3 trials and could enable global obesity submissions by year end