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Beyond radiosensitivity assessment, PDCOs are also proving useful in predicting responses to neoadjuvant chemoradiotherapy (nCRT)

Before this meta-analysis, the IM route was generally the preferred route, but our results showed that no route is usually preferred, and SL and oral routes should be considered comparable alternative routes

Common observations during this period include skin texture feeling slightly less plump or firm, fine lines that had completely disappeared beginning to reappear subtly, and overall skin quality remaining better than pre-treatment but noticeably less optimal than peak treatment results