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CYP enzyme activity is not influenced by tirzepatide according to the presently available study data and drug transporters are not inhibited (61)

It also lowered the secretion of cytokines IL-5 and IL-13 that belong to type 2 inflammation by ILC2s, suggesting that GLP-1R signaling may inhibit innate allergic immune responses in the lung [135]

Post-transplant diabetes mellitus is associated with worse liver allograft outcomes, including an increased risk of rejection and late-onset hepatic artery thrombosis