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Once the H 2 O 2 has been scavenged, GSH and GSSG levels behave as they do in the basic system (Fig

Impaired magnesium ion binding and carbohydrate kinase activities corresponded with dysfunctional RBKS and PRTFDC1, indicating TCA cycle disruption and mitochondrial oxidative phosphorylation inefficiency [63, 64]

Therefore, B12 deficiency should be excluded or treated before starting folic acid in patients with unexplained anaemia or neurological symptoms