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[323] found that oral administration of turmeric-derived nanoparticles with a specific population (TDNPs 2) in a mouse colitis model could improve gut inflammation and accelerate the resolution of colitis by regulating the expression of proinflammatory cytokines TNF-, IL-6 and IL-1 as well as the antioxidant gene HO-1

One theory suggests that the lipoprotein lipase acts on intravascular fat, generating FFAs that induce chemokine-derived cell infiltration, thereby damaging cell-capillary walls [15]

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On the other hand, excess vitamin B12 is expelled through urine, so there is little need to feel uneasy about injecting too much B12