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elegans germline, CYE-1 is critical for GLP-1-mediated germline proliferation (Fox et al., 2011), but CYD-1 is not (Fox et al., 2011)
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As the fourth selenoprotein in the glutathione peroxidase family, GPX4 (originally termed PHGPX for its phospholipid hydroperoxide-reducing capacity) serves as the unique enzymatic regulator of lipid peroxidation through its distinctive structural and functional properties (Xie et al., 2023)