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The nuclear factor erythroid 2-related factor 2 (Nrf2) pathway is a key transcription factor that regulates the expression of antioxidant-responsive genes, playing a crucial role in this process (168)

As outlined in this final rule, We are adopting the proposal for the Prescriber-Pharmacy Methodology to determine the total number of units of a Part D rebatable drug which will be considered 340B units and excluded when calculating a Part D inflation rebate as described at 428.203(b)(2) in order to implement section 1860D-14B(b)(1)(B) of the Act

For each animal, an average of the positive cell count was determined for both stomach regions