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Kidney transplantation can reduce plasma or serum TMAO levels, but to a lesser extent than other renal indices (Poesen et al., 2016

Without enough GLP-1 the brain cant be healthy

Massudi H, Grant R, Braidy N, Guest J, Farnsworth B, Guillemin GJ

Thus, more targeted, well-designed clinical trials are required for providing clearer evidence on the efficacy, optimal dose, and safety profiles of these drugs in AD and PD