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V.ShettyS.et al (2025)

Angioedema (swelling beneath the skin, often affecting the face or throat) is another possible manifestation of hypersensitivity that requires urgent medical attention

More recently, the same residue was mutated back to a non-acidic residue uniquely in legume plants, which resulted in prephenate-specific TyrA p enzymes (Schenck et al., 2017)