gila monster semaglutide venom… and weight loss? 🦎 It sounds wild, but it's true. GLP-1 medications were inspired by a hormone first discovered in the saliva of a Gila monster. On this week's The Gila Monster + GLP-1:

Participants (N=3417) were randomly assigned (21:3:3:7) to receive the combination of semaglutide 2.4 mg and cagrilintide 2.4 mg (n=2108), semaglutide 2.4 mg alone (n=302), cagrilintide 2.4 mg alone (n=302), or placebo (n=705), plus lifestyle interventions for all groups

The current FDA-approved GLP-1RAs are developed as analogues of either exedin-4 or GLP-1

Personalized Precision Peptide Testing for Optimal Response The PlexusDx Precision Peptide Genetic Test ($99 add-on after your first month) analyzes GLP1R (rs6923761), GIPR (rs1800437), FTO (rs9939609), and MC4R (rs17782313) variants that relate to GLP-1 and related signaling pathways

Oral lesions that could mimic canker sores include these conditions: (6,7,8) Leukoplakia These white spots in the mouth arent painful but could be precancerous