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364 Inducer specificity by CsoR-family repressors was originally described in the context of a simple W-X-Y-Z motif using the Mt CsoR Cu I chelate as a template, 203 where the first coordination shell ligands around a subunit-bridging, trigonally coordinated Cu I define the X (Cys36), Y (His61) and Z (Cys65) residue positions (Figure 12B)

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