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A growing body of evidence positions Alzheimer's disease as fundamentally a disorder of impaired brain energy metabolism, one in which neurons progressively lose the ability to utilize glucose efficiently, creating an energetic crisis that precedes structural damage by years or even decades

One technique measures the forearm blood flow by venous occlusion plethysmography during infusion of acetylcholine

Plaintiffs also allege that GlaxoSmithKline was actually aware that Zofran was unsafe for ingestion by pregnant women based on animal studies done in the 1980s, which revealed evidence of toxicity, intrauterine deaths, and malformations in offspring