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Moderate side effects of tirzepatide and semaglutide can include: constipation or diarrhea upset stomach, nausea, and vomiting headaches abdominal pain fatigue hypoglycemia (low blood sugar) More severe possible side effects of tirzepatide and semaglutide include: vision changes pancreatitis kidney failure gallbladder issues allergic reactions Both of these medications have boxed warnings about the risk of thyroid C-cell tumors

MOTS-c plays a role in mitochondrial biogenesis (new cell growth) which enhances cellular energy production and overall mitochondrial function

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