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Table 1: Evidence-Based Clinical Assessment Framework for Endometriosis Emerging Diagnostic Technologies and Approaches Advanced Imaging Techniques Three-dimensional ultrasound with volume analysis shows promise for detecting subtle endometriotic lesions not visible on conventional two-dimensional imaging

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Akt is the principal mediator of IGF-1s pro-survival, anti-apoptotic, and anabolic effects: it phosphorylates and inhibits pro-apoptotic factors, activates the mechanistic target of rapamycin complex 1 (mTORC1) to drive protein synthesis, and suppresses the FOXO transcription factors that promote muscle atrophy and proteolysis

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The promising results from the Phase III SOUL trial, which demonstrated a 14% reduction in MACE occurrence with Rybelsus, have further validated its role in cardiovascular disease prevention

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