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doi:10.1136/jech-2014-204971 [23] Cohen L, Jefferies A

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In general, the 3.0 and 4.5 g/d groups exhibited dramatically greater rates of DEC compared with baseline while the 1.5 g/d dosage resulted in greater resistance to fatigue on sprints 1 and 2 with more modest changes in DEC with sprints 3 -5

Without adequate methylation processes, the individual cannot adapt effectively and will suffer the deleterious effects of accelerated aging (1)