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Serum levels of IS and p-CS were significantly lowered, and data obtained indicated that the Lm-low dose group (10 7 CFUs) demonstrated greater efficacy in mitigating CKD progression and restoring the gut microbiota balance as against the Lm-high dose group (10 9 CFUs) (Huang et al., 2021)
Furthermore, iHLOs enable patient-specific modeling, providing a platform for precision medicine tailored to individual genetic and pathological conditions 12,13
Carr ER, Higgins PB, McClenaghan NH, Flatt PR, McCloskey AG (2024) MicroRNA regulation of islet and enteroendocrine peptides: physiology and therapeutic implications for type 2 diabetes
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