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Jong CJ, Sandal P, Schaffer SW

These results have implications for neuropsychiatric disorders characterized by accelerated aging molecular profiles, such as major depression

[13] The reasons for this positive selection are not known, but it has been hypothesized that elevated concentrations of acetaldehyde may have conferred protection against certain parasitic infections, such as Entamoeba histolytica

Efficacy of daily low-dose sildenafil for treating interstitial cystitis: results of a randomized, double-blind, placebo-controlled trial treatment of interstitial cystitis/painful bladder syndrome with low-dose sildenafil