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For most patients, sleep improves naturally without the need to discontinue treatment
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von Loeffelholz C, Docke S, Lock JF, Lieske S, Horn P, Kriebel J, Wahl S, Singmann P, de Las Heras Gala T, Grallert H, Raschzok N, Sauer IM, Heller R, Jahreis G, Claus RA, Bauer M, Stockmann M, Birkenfeld AL, Pfeiffer AFH (2017) Increased lipogenesis in spite of upregulated hepatic 5AMP-activated protein kinase in human non-alcoholic fatty liver
[18] [19] Their detoxification involves both broad-spectrum and specialized enzymatic systems, including families that act on reactive carbonyls and other electrophiles, as well as dedicated pathways for particularly toxic intermediates
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