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For instance, treatments with apple polysaccharides, flos lanicera, and Bofutsushosanan herbal remedy from Japanhave been successful in promoting the growth of beneficial bacteria like Lactobacillus and Bacteroidetes , improving intestinal barrier integrity, and decreasing pro-inflammatory cytokines such as TNF- and IL-6 [117,118,119]

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Therefore, it is not surprising that both ACE inhibitors and AT1 antagonists are effective in reducing OS on various cardiovascular diseases ( 5.1 Endothelial dysfunction Endothelial dysfunction and OS are inextricably linked in the pathophysiology of HTN, leading to vascular damage and elevated BP

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