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Tirzepatide, as a fully approved dual GLP-1/GIP agonist, has already transformed clinical practice and set a new benchmark for pharmacological weight management
Accordingly, while MI: DCI (40:1) appears more physiological for reproductive indications, DCI-leaning regimens may be better suited to metabolic priorities, underscoring the need for phenotype-driven therapeutic strategies (161, 163, 164)
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