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Many ongoing clinical trials, which evaluate clinical efficacy of NASH/NAFLD, are using imaging modalities using MRI-PDFF/MRE, which will become an alternative to liver biopsy

We find that the loss of GCLC across all tissues of adult animals results in rapid weight loss and death

Do not self-administer without professional direction

slower dose escalation Severity: Usually mild if you find your sweet spot dose Constipation More common than diarrhea Management: Increase fiber, water intake, magnesium glycinate Typically improves after 4-6 weeks Decreased Appetite (Intended) Some experience appetite too suppressed Management: Eat by the clock, not by hunger