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Edward John Pratt, orcid.org/0000-0003-4449-6231 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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The strongest risk occurred within the first year of treatment That timing may suggest an association between the drug and the sudden onset of optic nerve injury, though a retrospective cohort design cannot establish a definite causation

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