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(Selected Important Risk Information continues on the next page.) Before prescribing JANUVIA, please read the Prescribing Information

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Numerous skin aging treatments exist, and mostly consist of topical products (e.g., retinoids, -hydroxyacids, broad-spectrum sunscreens, and antioxidant/anti-inflammatory agents, such as preparations containing vitamin C, vitamin E, and niacinamide6) and invasive or minimally invasive procedures (e.g., ablative and nonablative laser therapy, intense pulsed light therapy, radiofrequency, dermabrasion, and chemical peels)