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The standard titration protocol Clinical trials used a gradual titration schedule, increasing the dose every four weeks to minimize gastrointestinal side effects

The cobalaminIF complex is a stable compound that can bind to specific receptors located on the microvilli of ileal enterocytes [22]

18-3 ), one sees that the G6P binding site is near K205, and the critical role of this amino acid in electron transfer has been confirmed by showing that replacing it with threonine nearly abolishes catalytic activity