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While FDA labeling includes no specific contraindication for inflammatory bowel disease, the medication's gastrointestinal side effectsincluding nausea, diarrhea, and abdominal painoverlap significantly with ulcerative colitis symptoms

That leaves a huge opening for GLP-1 supplement sellers to flood the $49.3 billion global market and convince consumers a $15 pack of unproven patches will yield the same results as brand-name drugs that have undergone comprehensive clinical trials, said Dr

Moreover, IBD patients exhibited lower prevalence of nausea, vomiting, and diarrhea, but increased rates of constipation (11%) in comparison to the general population (103)

We can see that the secretion of GLP-1 increases after adding berberine (Figure 6B)