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P53-mediated lipoxygenase and iPLA2 pathway As a tumor suppressor, p53 can inhibit tumor cells by arresting the cell cycle, promoting apoptosis and senescence [30, 31]
Among the pro-inflammatory cytokines induced in SARS-CoV-2 infection, tumor necrosis factor-alpha (TNF-), interleukin-6 (IL-6), IL-1, interferon- (IFN), monocyte chemoattractant protein 1 (MCP1), and granulocytemacrophage colony-stimulating factor (GM-CSF) stand out (Beltrn-Garca et al
The amyloid paradox: Amyloid--metal complexes be neurotoxic and neuroprotective
186 In fact, increased levels of cysteinyl-s-conjugates in biological fluids have been associated with several cancers, including melanoma, non-Hodgkin lymphoma, breast, ovarian and thyroid carcinomas, and with poor prognosis, recurrence and survival (see below)
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