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They also have far less impact on muscle growth or hormone levels

doi: 10.1111/dom.13218 18 PratleyREArodaVRLingvayILdemannJAndreassenCNavarriaAet al

The ideal margin for all forms of melanoma in situ is 5-10mm, depending on how well defined are the edges of the lesion

The biggest risk is something that can be called a silent restriction. When the medication mutes your stomachs physical hunger cues, its easy to accidentally slip into a state of under-fueling, which can be mimicking the very restrictive patterns that often trigger a binge cycle in the first place