why do i have diarrhea on tirzepatide and Diarrhea: Managing GLP-1 Digestive Side Effects Why Tirzepatide Causes Diarrhea |

Tirzepatide is a dual-receptor agonist, which means it mimics two natural hormones in your body: glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)

The activated signaling pathways promote the release of pro-inflammatory cytokines, leading to further aggravation of RA (227, 228)

They belong in the lifestyle and self-care space, alongside healthy eating habits, movement, hydration, and sleep

10 There have been no real-world studies, to our knowledge, evaluating prescribing practices and efficacy of tirzepatide in a cohort only with diabetes and chronic kidney disease to date