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In the presence of NADPH, labeling of TGR was more effective at both 5 and 50 M of PRP than that without NADPH, indicating a higher yield of TGR-PRP adduct when NADPH was present

Indeed, NRF2 can bind to the promoter regions of pro-inflammatory cytokines (e.g., IL-6 and IL-1), preventing the recruitment of RNA polymerase II and thus inhibiting their gene transcription (Kobayashi et al